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  • Title: [Reversed C.P.C.: Aggressive NK-cell leukemia/lymphoma].
    Author: Koyama T.
    Journal: Rinsho Byori; 2001 Mar; Suppl 115():140-3. PubMed ID: 11391932.
    Abstract:
    While natural killer(NK)-cell type granular lymphocyte-proliferative disorders(GLPD) generally represent benign disorders, acute NK-cell leukemia/lymphoma is a rare but a very aggressive disorder. We report a case characterized by an extranodal(nasal) and bone marrow infiltration of large granular lymphocyte morphology, CD3-CD16-CD56+ phenotype. The patient's course became severe and refractory. Multiorgan failure, associated with intravascular coagulation syndrome was the main cause of death.
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