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  • Title: [Anti-Coxsakie B viruses humoral immunity status in patients with pancreatic diseases].
    Author: Trukhan DI.
    Journal: Vopr Virusol; 2001; 46(2):33-6. PubMed ID: 11392968.
    Abstract:
    Similar titers and incidence of antibodies to group-specific Coxsackie B virus antigen were detected in 137 patients with chronic pancreatitis and 127 patients with insulin-dependent diabetes mellitus (IDDM). Characteristic clinical features of chronic pancreatitis associated with the presence of antibodies to Coxsackie B virus in high titers were detected. HLA Cw2 antigen is significantly more incident in the phenotype of patients with chronic pancreatitis and IDDM and high titers of antibodies to Coxsackie B virus. These data confirm the possible contribution of Coxsackie B virus infection to the development of IDDM and suggest its contribution to development of chronic pancreatitis.
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