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  • Title: Pressure-flow relationships in the peripheral circulation of the dog with isoprenaline.
    Author: Green JF.
    Journal: Clin Exp Pharmacol Physiol; 1975; 2(2):181-4. PubMed ID: 1139800.
    Abstract:
    1. The effects of isoprenaline on the pressure-flow relationships in the peripheral circulation were studied in five anaesthetized dogs during right heart bypass procedures. 2. Isoprenaline (1 mug/kg per min) produced a significant drop in arterial pressure and arterial resistance. 3. There was a significant decrease in the resistance to venous return which resulted in a significant increase in venous return. 4. The findings suggest that the increase in cardiac output produced by isoprenaline results in large part from dilatation of venous resistance vessels.
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