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  • Title: [1-(2-Diethylaminoethyl)-3,4-pentamethylenepyrazole and N2-substituted bornylenepyrazoles].
    Author: Schenone P, Longobardi M, Bondavalli F.
    Journal: Farmaco Sci; 1975 Jun; 30(6):456-63. PubMed ID: 1140382.
    Abstract:
    An unambiguous synthesis of 1-(2-diethylaminoethyl)-3,4-pentamethylenepyrazole (III) by acid cyclization of 2-(2-cycloheptanonyl)-1,3-dioxolane 2-diethylaminoethylhydrazone, and of N2-methyl and N2-(2-diethylaminoethyl)bornylenepyrazole (VIII) and (IX), by heating the hydrazones from 3-hydroxymethylene-2-bornanone and methylhydrazine or 2-diethylaminoethylhydrazine respectively, is described. (III) showed antiinflammatory activity and (VIII) an anticonvulsant action.
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