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  • Title: [Hypercalcemia due to immobilization in critically ill children: calcitnonin treatment].
    Author: Urán Moreno M, Alonso Riofrío R, Moliner Robredo C, Pons Morales S, López-Herce Cid J.
    Journal: An Esp Pediatr; 2001 Jun; 54(6):555-8. PubMed ID: 11412402.
    Abstract:
    OBJECTIVES: To evaluate the response to calcitonin treatment in critically ill children with hypercalcemia due to immobilization. PATIENTS AND METHODS: Four children aged 3-14 years were diagnosed with hypercalcemia due to immobilization. Detected levels of calcemia and ionic calcium ranged from 12.2-13.4 mg/dl and 1.44-2.2 mmol/l respectively. None of the children responded to rehydration or frusemide. Treatment was with subcutaneous and/or intranasal calcitonin at a dose of 6-20 IU /kg/day. RESULTS: After calcitonin administration, serum calcium decreased progressively until normal calcemia levels were reached between days 4 and 20 of treatment (8.6-10.5 mg/dl). No treatment-related adverse effects or alterations in phosphorus levels or alkaline phosphatases were observed. CONCLUSION: Calcitonin might be an effective treatment for hypercalcemia due to immobilization in critically ill children.
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