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  • Title: Infusion of the metabotropic receptor agonist, DCG-IV, into the main olfactory bulb induces olfactory preference learning in rat pups.
    Author: Rumsey JD, Darby-King A, Harley CW, McLean JH.
    Journal: Brain Res Dev Brain Res; 2001 Jun 29; 128(2):177-9. PubMed ID: 11412903.
    Abstract:
    DCG-IV, a type 2 metabotropic glutamate receptor (mGluR2) agonist, was infused into the main olfactory bulb of 1-week-old pups exposed to peppermint odor. A preference for peppermint was demonstrated 24 h later. The data support the proposal that disinhibition at dendrodendritic synapses between granule cells and mitral cells is a critical component of olfactory memory formation in the rat pup olfactory bulb as well as in the accessory olfactory bulb of adult rodents.
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