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  • Title: [Prognostication of obstructive syndrome in patients with chronic bronchitis considering hereditary factors].
    Author: Ivchik TV, Kokosov AN, Razorenov GI, Razorenova TS, Iakovleva NG.
    Journal: Ter Arkh; 2001; 73(3):33-7. PubMed ID: 11417177.
    Abstract:
    AIM: To propose method of accurate prediction of chronic obstructive pulmonary disease (COPD) at early stages of development. MATERIAL AND METHODS: 92 males with COPD and 55 males with chronic non-obstructive bronchitis aged 38 to 72 years were examined according to a technique which identifies hereditary predisposition to multifactor diseases and using an algorithm based on multivariate analysis. RESULTS: An original mathematical model is proposed which can quantitatively examine and range by influence the role of environmental and hereditary factors in development of COPD. CONCLUSION: Detection of hereditary predisposition to COPD may be one of the objective criteria to recommend giving up smoking and for occupational orientation.
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