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  • Title: Time of closure of ductus venosus in term and preterm neonates.
    Author: Kondo M, Itoh S, Kunikata T, Kusaka T, Ozaki T, Isobe K, Onishi S.
    Journal: Arch Dis Child Fetal Neonatal Ed; 2001 Jul; 85(1):F57-9. PubMed ID: 11420325.
    Abstract:
    AIM: To investigate the relation between gestational age, birth weight, and antenatal corticosteroid administration and the time of ductus venosus closure. METHODS: Ninety eight neonates of 30-41 weeks gestational age were studied by daily ultrasonography until ductus venosus closure. RESULTS: In neonates of 30-33 weeks gestational age, the ductus venosus closed at 6.0 (2.4)days (mean (SD)); in those of 34-36 weeks gestational age, it closed at 6.1 (2.8) days; and in those of 37-41 weeks gestational age, it closed at 4.2 (2.1) days. The effect of antenatal administration of corticosteroids on the time of closure was also investigated in neonates of 30-34 weeks gestational age. Closure occurred by 5.5 (2.4) days in the group given corticosteroids compared with 7.5 (2.1) days in the remainder. CONCLUSIONS: The ductus venosus closed sooner after birth in neonates of greater gestational age or higher birth weight. Antenatal corticosteroid administration had a significant effect in promoting closure.
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