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  • Title: Severe toxic hepatitis associated with amoxycillin and clavulanic acid.
    Author: Ersoz G, Karasu Z, Yildiz C, Akarca US, Yuce G, Batur Y.
    Journal: J Clin Pharm Ther; 2001 Jun; 26(3):225-9. PubMed ID: 11422607.
    Abstract:
    Toxic hepatitis secondary to amoxycillin-clavulanic acid is an infrequent clinical picture. Most of the cases are reported to have a benign course. We report two cases of severe hepatic failure following amoxycillin-clavulanic acid use. One of the cases had cholestatic features primarily, and the other had hepatocellular injury prominently. The first case had also findings of trombotic trombositic purpura and had a fatal course.
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