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Title: New bioactive sulfated metabolites from the Mediterranean tunicate Sidnyum turbinatum. Author: Aiello A, Carbonelli S, Fattorusso E, Iuvone T, Menna M. Journal: J Nat Prod; 2001 Feb; 64(2):219-21. PubMed ID: 11430005. Abstract: In addition to the known sodium 3,7,11,15-tetramethylhexadeca-1,19-diyl sulfate (4), the BuOH extract of the Mediterranean tunicate Sidnyum turbinatum was shown to contain four new metabolites: 1-heptadecanyl sulfate (1), 1-octadecanyl sulfate (2), sodium (2S)-2,6,10,14-tetramethylpentadeca-1,18-diyl sulfate (3), and 1-hexyl sulfate (5). Their structures were determined by spectroscopic and chemical methods. Compounds 1-5 exhibited in vitro antiproliferative activity estimated on the WEHI 164 cell line.[Abstract] [Full Text] [Related] [New Search]