These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Sox9 induces testis development in XX transgenic mice.
    Author: Vidal VP, Chaboissier MC, de Rooij DG, Schedl A.
    Journal: Nat Genet; 2001 Jul; 28(3):216-7. PubMed ID: 11431689.
    Abstract:
    Mutations in SOX9 are associated with male-to-female sex reversal in humans. To analyze Sox9 function during sex determination, we ectopically expressed this gene in XX gonads. Here, we show that Sox9 is sufficient to induce testis formation in mice, indicating that it can substitute for the sex-determining gene Sry.
    [Abstract] [Full Text] [Related] [New Search]