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  • Title: [Evaluation of oxalate/creatinine ratio in the second morning urine sample of health school children].
    Author: Sikora P, Zajaczkowska M, Zinkiewicz Z, Wawrzyszuk T.
    Journal: Pol Merkur Lekarski; 2001 Apr; 10(58):271-3. PubMed ID: 11434174.
    Abstract:
    The evaluation of urinary oxalate excretion is one of the most important diagnostic methods in patients with urolithiasis and/or nephrocalcinosis. Since reliable 24-h urine collections are difficult to obtain in children, excretion ratios of oxalate over creatinine are increasingly being used from single urine specimens. The aim of the study was to determine the normal values of oxalate/creatinine ratios in the second morning urine sample in healthy school children. The study involved 109 children between 6 and 16 years of age. The results showed that the values of Ox/Cr ratios are decreased in older children and there was significant difference between children under and above 12 years of age (values of the 95th percentile--0.076 and 0.051 mmol/mmol respectively). The significant correlation between 24-hours urinary oxalic acid excretions and Ox/Cr ratios (r-0.756) was found. We conclude, that Ox/Cr ratio is valuable parameter for screening purposes in children.
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