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  • Title: Angiosarcoma variant of Kasabach-Merritt syndrome.
    Author: Alliot C, Tribout B, Barrios M, Gontier MF.
    Journal: Eur J Gastroenterol Hepatol; 2001 Jun; 13(6):731-4. PubMed ID: 11434603.
    Abstract:
    Kasabach-Merritt syndrome is characterized by the occurrence of disseminated intravascular coagulation (DIC) usually caused by benign angiomatous tumours. Here we report the case of a 70-year-old man in whom DIC revealed a locally advanced hepatic tumour. Although DIC resolved with heparin, antithrombin III, fresh frozen plasma and corticosteroids, the patient died from haemoperitoneum following a fall, 3 months after the initial observation. Histopathological examination by autopsy allowed the diagnosis of hepatic angiosarcoma. The physiopathogenic mechanisms and treatment options are discussed.
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