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  • Title: Anti-plaque efficacy of a chalk-based antimicrobial dentifrice.
    Author: Lewis RD, Marken BF, Smith SR.
    Journal: SADJ; 2001 Apr; 56(4):178-81. PubMed ID: 11436232.
    Abstract:
    A chalk-based antimicrobial dentifrice was developed and has undergone in vitro testing to determine antimicrobial efficacy by kill-time studies, and in vivo clinical studies to determine anti-plaque build-up properties. The antimicrobial efficacy of the formulation is attributable to the following components; sodium lauryl sulphate, sodium monofluorophosphate, flavouring oils, triclosan, and low water activity. In vitro kill-time testing showed the dentifrice to have good activity against organisms associated with plaque, showing at least 99% reductions in the numbers of each organism. In vivo clinical results showed the dentifrice to protect against the build-up of plaque when compared to water alone. These results demonstrate that this dentifrice is effective in controlling plaque, and can thus be expected to promote good oral hygiene.
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