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  • Title: Acute hemolysis and severe neonatal hyperbilirubinemia in glucose-6-phosphate dehydrogenase-deficient heterozygotes.
    Author: Kaplan M, Hammerman C, Vreman HJ, Stevenson DK, Beutler E.
    Journal: J Pediatr; 2001 Jul; 139(1):137-40. PubMed ID: 11445808.
    Abstract:
    Two premature female infants had severe hyperbilirubinemia caused by hemolysis. Both neonates were heterozygotes for the glucose-6-phosphate dehydrogenase Mediterranean mutation as determined by DNA analysis. Glucose-6-phosphate dehydrogenase-deficient heterozygotes may be susceptible to the complications of this enzyme deficiency.
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