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  • Title: Effects of female sex hormones on uterine motility and reactivity to oxytocin in goats.
    Author: Jones DE, Knifton A.
    Journal: Res Vet Sci; 1975 May; 18(3):288-93. PubMed ID: 1144921.
    Abstract:
    Uterine motility was recorded for several weeks in 10 ovariectomised goats, using small intra-uterine balloons, to study the effects of female sex hormones on uterine activity and reactivity to oxytocin. Oestradiol stimulated uterine contractions and increased both the sensitivity and intra-uterine pressure response to oxytocin. When progesterone was administered in addition to oestradiol, spontaneous uterine motility became irregular with low amplitude contrations; the sensitivity and reactivity to oxytocin was significantly depressed.
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