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  • Title: [Nephrogenic adenoma of the bladder: metaplasia or embryologic alteration?].
    Author: Sousa Escandón MA, Pérez Valcárcel J, González Fernández M, González Rodríguez A, Lapeña Villarroya JA, Uribarri González C.
    Journal: Actas Urol Esp; 2001 Apr; 25(4):307-11. PubMed ID: 11455835.
    Abstract:
    OBJECTIVES: To present a new case of nephrogenic adenoma of the bladder and to review the current concepts on the etiopathogenesis of this lesion. CLINICAL CASE: Seventy years old female with repetitive haematuria who was diagnosed as having a nephrogenic adenoma of the bladder which was extirpated by cold biopsy forceps. No tumoral relapse was detected after 16 months of follow up. DISCUSSION: In the light of the present knowledges, the origin of nephrogenic adenoma is a phenomenon of urothelial metaplasia due to a chronic irritative stimulus wich would lead a cellular proliferation with potentialities to originate mesonephric tissues and which starting point could be on not completely involutioned mesonephric cellular rests and/or on de-differentiated mature urothelial cells.
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