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  • Title: The value of D1 lymphadenectomy as prognostic marker in gastric cancer.
    Author: Diaz de Liaño A, Ciga MA, Oteiza F, Aizcorbe M, Cobo F, Trujillo R, Nuin MA.
    Journal: Hepatogastroenterology; 2001; 48(39):895-8. PubMed ID: 11462951.
    Abstract:
    BACKGROUND/AIMS: To assess if the study on the involvement of perigastric lymph nodes, the only ones resected in D1 lymphadenectomy, is a valid prognostic marker in patients undergoing curative resection for gastric cancer. METHODOLOGY: A retrospective study was performed in 101 patients with gastric cancer, 34 women and 67 men, with a mean age of 61 years, undergoing curative resection by gastrectomy and D1 lymphadenectomy. Tumor size, the depth of tumoral invasion of the wall, nodal involvement and 5-year survival were assessed. RESULTS: Both tumor size and the depth of tumoral invasion of the wall were significantly related to metastatic involvement of perigastric lymph nodes. Similarly, tumoral involvement of the first-level lymph nodes was significantly associated with survival. CONCLUSIONS: D1 lymphadenectomy can provide adequate prognostic information in patients with gastric cancer undergoing curative resection.
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