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  • Title: Dense inflammation does not mask residual primary basal cell carcinoma during Mohs micrographic surgery.
    Author: Katz KH, Helm KF, Billingsley EM, Maloney ME.
    Journal: J Am Acad Dermatol; 2001 Aug; 45(2):231-8. PubMed ID: 11464184.
    Abstract:
    BACKGROUND: Areas of dense inflammation are commonly removed during Mohs micrographic surgery for basal cell carcinoma because of the concern that they may mask areas of tumor. OBJECTIVE: Our purpose was to determine whether inflammation masks tumor during Mohs surgery for primary basal cell carcinoma. METHODS: Twenty-five consecutive cases of primary basal cell carcinoma with areas of dense inflammation encountered during Mohs surgery were sectioned and stained with hematoxylin and eosin and Ber-EP4. RESULTS: In no cases did the dense inflammation mask residual tumor. CONCLUSION: Dense inflammation does not mask primary basal cell carcinoma during Mohs surgery and should be carefully evaluated before additional surgery is performed.
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