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  • Title: Pigmented neurofibroma: report of two cases and literature review.
    Author: Inaba M, Yamamoto T, Minami R, Ohbayashi C, Hanioka K.
    Journal: Pathol Int; 2001 Jul; 51(7):565-9. PubMed ID: 11472571.
    Abstract:
    Two cases of pigmented neurofibroma of the skin are reported. In case 1, the tumor was removed from the back of a 55-year-old man with no associated neurofibromatosis. In case 2, the tumor was removed from the abdominal wall of a 21-year-old woman with neurofibromatosis. Both tumors consisted of benign, short spindle cells and multiple foci of scattered melanin-laden cells. In case 1, the spindle cells were arranged in a storiform pattern, resembling features of dermatofibrosarcoma protuberans. Immunohistochemically, the spindle cells of both cases were demonstrated to be positive for S-100 protein and CD34. The melanin-laden cells stained positively for HMB-45. This report describes an additional two cases of pigmented neurofibroma that conform to the new diagnostic criteria for this disease.
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