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  • Title: Q fever (Coxiella burnetii) investigations in dairy cattle: persistence of antibodies after vaccination.
    Author: Behymer DE, Biberstein EL, Riemann HP, Franti CE, Sawyer M.
    Journal: Am J Vet Res; 1975 Jun; 36(6):781-84. PubMed ID: 1147331.
    Abstract:
    The immune response and persistence of antibodies were investigated in dairy cattle vaccinated with formalin-inactivated phase (ph) I Coxiella burnetii vaccine agglutinating antibody geometric mean titer (GMT) of 193.2 at 1 month after vaccination compared to a GMT of 2.0 for nonvaccinated calves. The agglutinating antibodies gradually decreased in vaccinated cattle, but the GMT remained approximately 4 times higher than that for the nonvaccinated group for at least 20 months. Results of serotests at 2 months after revaccination indicated a rapid increase in the GMT to 177.0 with agglutinating titers between 1:64 and 1:512.
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