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  • Title: [Hypoglycemic treatment of type 2 diabetes].
    Author: Thorsby P, Kilhovd B, Sletmo R, Martinsen S, Birkeland KI.
    Journal: Tidsskr Nor Laegeforen; 2000 Aug 30; 120(20):2434-40. PubMed ID: 11475233.
    Abstract:
    BACKGROUND: Hyperglycaemia in type 2 diabetes results from reduced beta-cell function and insulin resistance. The treatment of type 2 diabetes must be targeted against both conditions to reduce symptoms of hyperglycaemia and the risk of diabetic late complications. MATERIAL AND METHODS: In this review we cover the recent scientific documentation from long term studies on treatment effects. We also discuss the different treatments available. RESULTS: Recent clinical trials have shown that lowering blood glucose levels over time significantly reduces development of microvascular complications in type 2 diabetes. There are several treatment options available which make adequate blood glucose control possible in patients with type 2 diabetes. INTERPRETATION: A reduction in the development of microvascular complications in type 2 diabetes is an achievable goal.
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