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  • Title: [Efficacy and safety of intravenously administered pantoprazole in the treatment of gastrinoma].
    Author: Modlin IM.
    Journal: Recenti Prog Med; 2001; 92(7-8):456-61. PubMed ID: 11475787.
    Abstract:
    The efficacy and safety of the proton pump inhibitor pantoprazole (P) in patients with Zollinger-Ellison syndrome (ZES) is well documented. We treated 21 patients with ZES with intravenous P; 13 of these patients were treated surgically in advance. The effect of P was very rapid, with reduction of the acid output within 15 min and its normalization within 60 min. The control of gastric acid secretion was maintained for a mean of 10.9 hours after the infusion of P. We conclude that the use of intravenous P allows a safe and efficient control of the acid ipersecretion in patients with ZES.
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