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  • Title: [MRI finding of CNS cryptococcosis in an HIV-positive patient].
    Author: Mandokoro H, Tokuoka K, Ohnuki Y, Takizawa S, Shinohara Y.
    Journal: Rinsho Shinkeigaku; 2001; 41(2-3):154-6. PubMed ID: 11481862.
    Abstract:
    We report an HIV-positive patient with CNS cryptococcosis, diagnosis of which was based on detection of Cryptococcus neoformans by Indian ink staining and culture of CSF. MRI displayed dilated Virchow-Robin space in bilateral basal ganglia which were hypointense on T1-weighted images, hyperintense on T2-weighted images, and enhanced by gadolinium administration. In addition cryptococcoma in the cerebellum was observed by MRI. This finding may suggest a progression from cryptococcal meningitis to intraparenchymal invasion, accompanied with breakdown of the blood brain barrier.
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