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  • Title: Purification and characterization of an aminoacyl proline hydrolase from guinea-pig intestinal mucosa.
    Author: O'Cuinn G, Fottrell PF.
    Journal: Biochim Biophys Acta; 1975 Jun 24; 391(2):388-95. PubMed ID: 1148215.
    Abstract:
    The purification of an aminoacylproline hydrolase from guinea-pig intestinal mucosa is described. The enzyme, which is an aminopeptidase has a molecular weight of 112 000 and is activated by manganese and inhibited by zinc. Unlike other aminoacylproline hydrolases this enzyme displayed a broad substrate specificity. However, it was preferentially active against dipeptides containing proline in the C-terminal position.
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