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  • Title: A case of an ameloblastic fibro-odontoma arising from a calcifying odontogenic cyst.
    Author: Matsuzaka K, Inoue T, Nashimoto M, Takemoto K, Ishikawa H, Asaka M, Shimono M, Fujikawa M, Noma H.
    Journal: Bull Tokyo Dent Coll; 2001 Feb; 42(1):51-5. PubMed ID: 11484795.
    Abstract:
    This case report describes an ameloblastic fibro-odontoma arising from a calcifying odontogenic cyst (COC) in the mandible of a twenty-three-year old male. The patient was referred to the Department of Oral Surgery, Tokyo Dental College, on March 30th, 2000, complaining of a painful swelling, which had appeared three weeks earlier on his left mandibular molar region. In a pathological view, the lesion was a round cyst the size of a chicken-egg, dark red in color, and surrounded by a thick membrane. The cyst had an epithelium of varying thickness which included many ghost cells and an enamel-like structure on the inside, and a thick wall of connective tissue with an ameloblastic fibro-odontoma on the outside. Enamel organ-like epithelial islands were structured radially in the form of strands with immature dentin. Cytokeratin 19 was strongly immunoreactive in the epithelium of the lesion; osteopontin and osteocalcin reacted in the mesenchymal cells and weakly in the epithelial element of this tumor.
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