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  • Title: [Cerebral toxoplasmosis in HIV infected patients intolerant of cotrimoxazole].
    Author: Rabaud C, May T, Beuscart C, Reynes J, Leport C, Canton P.
    Journal: Ann Med Interne (Paris); 1998 Mar; 149(2):62-6. PubMed ID: 11490526.
    Abstract:
    Using results of a multicentric randomized prospective trial of primary prophylaxis of Pneumocystis carinii pneumonia in HIV-infected patients which compared sulfamethoxazole-trimethoprim and pentamidine isethionate, the risk to develop cerebral toxoplasmosis was analyzed in the two assigned groups and in the groups of patients who stopped sulfamethoxazole-trimethoprim prophylaxis. The risk to develop cerebral toxoplasmosis appeared significantly higher in the group of patients who stopped sulfamethoxazole-trimethoprim consecutively to cutaneous hypersensitivity.
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