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  • Title: [Cerebrogenic cardiac arrhythmia in patients with organic brain diseases of nonvascular genesis].
    Author: Sin'kova GM, Dzizinskiĭ AA, Shprakh VV, Sink'kov AV.
    Journal: Klin Med (Mosk); 2001; 79(4):13-7. PubMed ID: 11496730.
    Abstract:
    Cardiological examination covered 115 patients (79 males and 36 females aged 16-44 years) with organic brain pathology of nonvascular genesis: epilepsy (n = 51), sequelae of closed craniocerebral trauma (n = 37) or cerebral inflammation (n = 27). The control group consisted of 15 healthy subjects. It was found that patients with brain diseases have a variety of cardiac rhythm and conduction disturbances which occur much more often than in the control group (p < 0.01). Cardiac arrhythmia was encountered most often in epileptics and patients with complications of closed craniocerebral trauma (96.1% and 70.3%, respectively). Rates of cardiac arrhythmia and conduction disorders in patients with brain diseases correlated with frequency of epileptic fits and severity of organic alterations in the brain. The pattern of rhythmic and conduction disorders was formed according to dysfunction of suprasegmentary vegetative centers with prevalent activation of the sympathetic or parasympathetic autonomic nervous system. Cardiac arrhythmia and related negative feelings deteriorate "quality of life" in patients with brain pathology that's why it is necessary to detect and treat them early.
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