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  • Title: [Repair of rabbit auricular defects using chondrocyte-scaffolding constructs].
    Author: Liu Y, Wang W, Cao Y.
    Journal: Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi; 1999 May; 15(3):180-2. PubMed ID: 11501115.
    Abstract:
    OBJECTIVE: To evaluate if the tissue-engineered cartilage can repair the auricular defects in rabbits that have inherent immunity. METHODS: Rabbit auricular defects were repaired using chondrocyte-PGA constructs cultured in vitro. The gross and histological comparisons were made between the experimental and the control groups. RESULTS: The rabbit auricular defects were repaired with chondrocyte-PGA constructs, leaving fibroid tissue in the interface between the tissue-engineered cartilage and the normal cartilage. CONCLUSION: The auricular defects can be repaired by chondrocyte-PGA in vitro cultured constructs in animals like rabbits that have acquired immunity. The interface healing problems need further study.
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