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  • Title: Synthesis and enzymatic evaluation of mucin type core 4 O-glycan.
    Author: Misra AK, Ujita M, Fukuda M, Hindsgaul O.
    Journal: Carbohydr Lett; 2001; 4(2):71-6. PubMed ID: 11506160.
    Abstract:
    Lactosylaminylated core-4 tetrasaccharide found in mucin type O-glycans has been synthesized . The non-reducing galactose residue of the deblocked tetrasaccharide was removed by beta-galactosidase from E. coli to produce the corresponding GlcNAc terminated compound. The core-2 and core-4 tetrasaccharides were evaluated as acceptors for the beta-1,3-N-acetylglucosaminyltransferase (iGnT), beta-1,4-Galactosyltransferase IV(beta4GalTIV) and beta-1,4-Galactosyltransferase I(beta4GalTI).
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