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  • Title: Low-dose zinc administration as an effective Wilson's disease treatment.
    Author: Najda J, Stella-Hołowiecka B, Machalski M.
    Journal: Biol Trace Elem Res; 2001 Jun; 80(3):281-4. PubMed ID: 11508632.
    Abstract:
    A case of a 11-yr-long Wilson's disease treatment in a 16-yr-old boy with neurologic presentation was analyzed and monitored. In the face of severe symptoms of chelator intolerance, a comparatively low dose of 100 mg of zinc has been administered for the entire 11-yr-long treatment. Considerable improvement of clinical status was achieved, with accompanying regression of central nervous system lesion. The parameters of copper metabolism were normalized with effective urine elimination. The low-dose oral zinc intake proved to be therapeutically effective, eliminating further copper tissue toxicity.
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