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  • Title: [Causes of lethal outcomes in croup syndrome in children].
    Author: Savenkova MS, Korobko LM, Kotsyganova GG, Legkova TP, Afanas'eva AA, Golubtsova EE.
    Journal: Vestn Otorinolaringol; 2001; (3):50-1. PubMed ID: 11510049.
    Abstract:
    The paper reports 40 cases of lethal outcomes in children with croup syndrome treated in Morozov Children's Moscow City Hospital in 1985-1998. 92.5% of them died of severe pneumonia complications, 7.5%--of sepsis. 70% of the deceased were infants aged 0-2 years, 75% of them were boys. All the children had aggravated premorbid background. The sputum and organ tissues contained in most cases association of viruses with staphylococci and streptococci resistant to standard antibiotics (penicillin, ampicillin, cefazoline). The conclusion is made that children with croup died primarily of severe pneumonia complications in low systemic reactivity and bacterial-viral association of the agents resistant to the antibacterial therapy.
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