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  • Title: Microchromatography of hemoglobins. IV. An improved procedure for the detection of hemoglobins S and C at birth.
    Author: Schroeder WA, Huisman TH, Powars D, Evans L, Abraham EC, Lam H.
    Journal: J Lab Clin Med; 1975 Sep; 86(3):528-32. PubMed ID: 1151168.
    Abstract:
    Substitution of CM-cellulose for CM-Sephadex had yielded a superior microchromatographic method for distinguishing the AS, AC, SS, SC, and CC conditions at birth. On the translucent columns of CM-Sephadex, the hemoglobin zones are somewhat diffuse. However, the compact, well-defined zones on the CM-cellulose column facilitate the interpretation of the results even though the amount of sample is only 20 per cent as great. The CM-cellulose method is as simple and rapid as the original CM-Sephadex procedure.
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