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  • Title: A simple procedure for synthesis of roxindole, a dopamine D2-receptor agonist.
    Author: Csende F.
    Journal: Arch Pharm (Weinheim); 2001 Jul; 334(7):253-4. PubMed ID: 11512277.
    Abstract:
    A modified convenient and high yielding synthetic route for the preparation of the dopamine agonist roxindole 1 is described. The key step in our method is the phase-transfer catalyzed reaction of gamma-butyrolactone with 5-methoxyindole which results in the indolylbutyric acid derivative directly in one step.
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