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  • Title: Isolated marrow reticuloendothelial activation and erythropoietic response following an acute blood loss.
    Author: Okuyama S, Sato T, Takahashi K, Ito Y, Matsuzawa T.
    Journal: J Reticuloendothel Soc; 1975 Jun; 17(6):353-60. PubMed ID: 1151948.
    Abstract:
    The radioassay technique with the 113mIndium-iron chondroitin sulfate colloid, developed in our laboratory, revealed that an isolated marrow reticuloendothelial activation takes place after bleeding 15 to 30 ml of blood per kg body weight from a rabbit. It parallels the erythropoietic response very well. The present stimulation method might deserve testing for studies where marrow reticuloendothelial function is important such as in cancer-bearing patients, the effects of anticancer chemotherapy and gross antigenization.
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