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Title: Discriminable effects of benzodiazepines. Author: Overton DA. Journal: Psychopharmacol Commun; 1976; 2(4):339-43. PubMed ID: 11529. Abstract: In a shock-escape T-maze task, rats rapidly discriminated diazepam, flurazepam and chloridazepoxide from no drug. The discriminable effects of these benzodiazepines were not completely interchangeable with those of barbiturate anesthetics. The dose-response curve for diazepam asymptoted over the range 15 to 100 mg/kg, ip whereas dose-response curves for flurazepam and chloridazepoxide were more linear.[Abstract] [Full Text] [Related] [New Search]