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  • Title: Effects of hindlimb suspension training on the central and regional hemodynamic responses during 24 hours antiorthostatic hypokinesia in the awake rat.
    Author: Bytchkova EY, Medvedev OS, Matsievsky DD, Krotov VP.
    Journal: J Gravit Physiol; 1994 May; 1(1):P137-8. PubMed ID: 11538743.
    Abstract:
    To date the hindlimb suspension model utilizing rats has a wide application to simulate weightlessness. In our previous study we have examined the cardiovascular responses in the tail suspension model using the radiolabeled microspheres technique. We have reported increases of cardiac output (CO) and decreases of total peripheral vascular resistance (TPVR) after 24 hours of head-down tilt (HDT). However, there is no comparison of arterial and venous systems parameters with blood flow changes in organs and tissues. Apart from the preliminary HDT training influence on these parameters is unknown. Thus we aimed to evaluate the role of HDT training in central circulation responses, venous tone and regional blood flow.
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