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  • Title: Influence of performance on gene expression in skeletal muscle: effects of forced inactivity.
    Author: Thomason DB, Booth FW.
    Journal: Adv Myochem; 1989; 2():79-82. PubMed ID: 11540914.
    Abstract:
    Joint immobilization and hindlimb suspension are used to examine muscle protein expression and mRNA quantities in rats. A decrease in protein synthesis was not associated with alteration in alpha-actin mRNA, cytochrome c mRNA, or beta-myosin heavy chain mRNA early in treatment. Percentage declines after seven days are compared with early treatment quantities to determine acute and chronic response to muscular atrophy.
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