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  • Title: Endothelial cell ischemic injury: protective effect of heparin or aspirin assessed by scanning electron microscopy.
    Author: Gertz D, Rennels ML, Nelson E.
    Journal: Stroke; 1975; 6(4):357-60. PubMed ID: 1154471.
    Abstract:
    Scanning electron microscopic observations of the luminal surface of the rabbit common carotid artery subjected to occlusion for 30 minutes or two hours revealed crater-like and balloon-like defects in the endothelial surface. The frequency of occurrence of these abnormalities was significantly decreased by pretreatment with heparin or aspirin in doses considered to have antiplatelet aggregating activity.
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