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  • Title: Immunology. Long live the mature B cell--a baffling mystery resolved.
    Author: Waldschmidt TJ, Noelle RJ.
    Journal: Science; 2001 Sep 14; 293(5537):2012-3. PubMed ID: 11557866.
    Abstract:
    What determines whether transitional B cells newly emerged from the bone marrow will differentiate further to become mature, long-lived, circulating B lymphocytes? In a Perspective, Waldschmidt and Noelle discuss new findings showing that the TNF family ligand BAFF and its receptor BAFF-R are crucial for selecting transitional B cells into the mature B cell pool (Thompson et al., Schiemann et al.).
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