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  • Title: Base mutation analysis by a ferrocenyl naphthalene diimide derivative.
    Author: Takenaka S, Miyahara H, Yamashita K, Takagi M, Kondo H.
    Journal: Nucleosides Nucleotides Nucleic Acids; 2001; 20(4-7):1429-32. PubMed ID: 11563037.
    Abstract:
    An electrochemical DNA sensing technique was developed by using ferrocenyl naphthalene diimide coupled with a probe DNA-immobilized electrode. This technique enabled detection of target DNA quickly and with high sensitivity. Applicability of this technique for single nucleotide polymorphisms (SNPs) analysis was demonstrated by successful analysis of a DNA mismatch on the cancer repression gene p53 with high precision.
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