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Pubmed for Handhelds

PUBMED FOR HANDHELDS

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  • Title: Recognition of DNA by strand invasion with oligonucleotide-spermine conjugates.
    Author: Potier PF, Behr JP.
    Journal: Nucleosides Nucleotides Nucleic Acids; 2001; 20(4-7):809-13. PubMed ID: 11563121.
    Abstract:
    Modified oligonucleotides bearing spermine groups (ODN-sper) with increased binding affinity to DNA have been synthesized. The ability of these ODN-sper to bind within superhelical double-stranded DNA by strand invasion has been studied. The uptake by a supercoiled plasmid was 3 fold higher for the ODN-sper than for the unmodified oligonucleotides.
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