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  • Title: Effect of allylisopropylacetamide on Nuclear Ribonucleic Acid synthesis in rat liver.
    Author: Sardana MK, Satyanarayana Rao MR, Padmanaban G.
    Journal: Biochem J; 1975 Apr; 147(1):185-6. PubMed ID: 1156384.
    Abstract:
    The porphyrogenic drug allylisopropylacetamide, a potent inducer of delta-aminolaevulinate synthetase, specifically increases nucleoplasmic RNA synthesis in rat liver. The drug-mediated increase in nucleoplasmic RNA synthesis is blocked by cycloheximide and haemin, which also inhibit the enzyme induction.
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