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  • Title: Biosynthesis of 17beta-oestradiol in human breast carcinoma tissue and a novel method for its characterization.
    Author: Adams JB, Li K.
    Journal: Br J Cancer; 1975 Apr; 31(4):429-33. PubMed ID: 1156524.
    Abstract:
    Conversion of 7alpha3H-testosterone to 17beta-oestradiol by human mammary carcinoma tissue in vitro has been demonstrated. It was characterized unequivocally by conversion to 17beta-oestradiol-3-sulphate upon incubation with adenosine-3'-phosphate-5'-phosphosulphate and the highly specific enzyme oestrogen sulphotransferase.
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