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  • Title: Pulmonary mechanics in diffuse fibrosing alveolitis.
    Author: Yernault JC, de Jonghe M, de Coster A, Englert M.
    Journal: Bull Physiopathol Respir (Nancy); 1975; 11(2):231-44. PubMed ID: 1156719.
    Abstract:
    The mechanical and the diffusing lung properties have been measured in 19 cases of diffuse fibrosing alveolitis of unknown etiology (proved by histology in 17 cases). The characteristic findings are: a) a striking reduction of DLCO in all the cases; b) a marked reduction of the static and dynamic compliance, in correlation with the reduction of vital capacity; c) an increase in P1max in correlation with the decrease of FRC; d) an increase of the elastic recoil when it is considered at various percentages of the predicted lung volume, but in some cases a normal shape of the V-P curve if the measured lung volume is taken into account; e) a reduction of the maximum expiratory flows suggesting bronchiolar stenosis; f) alterations of DL more marked than those of CL suggesting that DL is a more sensitive test.
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