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  • Title: Studies on the synthesis and biological activity of 3-arylaminomethyl-5-(3-pyridyl)-1,3,4-oxadiazole-2-thione derivatives.
    Author: Satyanarayana D, Gorge S, Subrahmanyam EV, Kalluraya B.
    Journal: Boll Chim Farm; 2001; 140(4):228-32. PubMed ID: 11570218.
    Abstract:
    3-arylaminomethyl-5-(3-pyridyl)-1,3,4-oxadiazole-2-thiones were prepared by reaction of 5-(3-pyridyl)-1,3,4-oxadiazole-2-thione with formaldehyde and appropriate alky and aryl amines in ethanol, as potential biological active agents. These new synthesized Mannich bases were screened for their antimicrobial, antifungal and antiinflammatory activities.
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