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  • Title: The alkaloids of Artabotrys uncinatus.
    Author: Hsieh TJ, Chang FR, Chia YC, Chen CY, Lin HC, Chiu HF, Wu YC.
    Journal: J Nat Prod; 2001 Sep; 64(9):1157-61. PubMed ID: 11575948.
    Abstract:
    A novel type of alpha,beta-butenolide alkaloid, uncinine (1), two novel oxoaporphines, artabonatine C (2) and artabonatine D (3), a new oxazoloaporphine, artabonatine E (4), and a new 7,7'-bisdehydroaporphine, artabonatine F (5), along with 25 known alkaloids, were isolated from Artabotrys uncinatus. The structures of 1-5 were determined using NMR and mass spectral data. Atherospermidine and squamolone exhibited cytotoxicity against hepatocarcinoma cancer cell lines (Hep G(2) and 2,2,15), and the activity of some of the alkaloids in an antithrombin assay is also discussed.
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