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  • Title: [Effect of somatostatin on betazole-stimulated gastric secretion and carbachol-stimulated pancreatic secretion and gall bladder contraction in man(author's transl)].
    Author: Lankisch PG, Arnold R, Creuzfeldt W.
    Journal: Dtsch Med Wochenschr; 1975 Sep 05; 100(36):1797-800. PubMed ID: 1157680.
    Abstract:
    The effect of somatostatin on betazole-stimulated gastric secretion and carbachol-stimulated pancreatic secretion and gall bladder contraction has been studied in seven healthy volunteers. Somatostatin (150 and 250 mug/h) inhibited dose-dependently volume of gastric juice and acid output stimulated by 16 mg betazole. Acid concentration was little affected. 500 mug/h were not more effective than 250 mug/h. Pancreatic secretion stimulated by 250 mug carbachol has been reduced by 80-90% and gall bladder contraction abolished by somatostatin infusion (200 mug/h).
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