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  • Title: Wegener's granulomatosis presenting as acute suppurative interstitial nephritis.
    Author: Banerjee A, McKane W, Thiru S, Farrington K.
    Journal: J Clin Pathol; 2001 Oct; 54(10):787-9. PubMed ID: 11577128.
    Abstract:
    A 78 year old man presented with acute renal failure following a prolonged respiratory illness. A renal biopsy demonstrated severe suppurative interstitial nephritis with normal glomeruli. After nine weeks of antibiotics he remained anuric and a second biopsy demonstrated pauci-immune, necrotising glomerulonephritis. His subsequent clinical course was consistent with a diagnosis of Wegener's granulomatosis and antineutrophil cytoplasmic antibodies (ANCA) were detected. This is the first reported case of Wegener's granulomatosis presenting with an isolated tubulointerstitial lesion.
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