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Title: Of mice, men and motor neurons. Author: Newbery HJ, Abbott CM. Journal: Trends Genet; 2001 Oct; 17(10):S2-6. PubMed ID: 11585669. Abstract: The use of mouse models has been of particular importance in studying the pathogenesis of amyotrophic lateral sclerosis. Here, we describe both transgenic and classical mutants for which the genetic lesion is known. We draw attention, wherever possible, to pathological factors common to multiple models.[Abstract] [Full Text] [Related] [New Search]